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EU-TIRADS SCORE

 

The EU TIRADS score Acronym for: European Thyroid Imaging-Reporting and Data System: is a method implemented by the European Thyroid Association in 2017.

The objective of allowing reproducible analysis of thyroid nodules on ultrasound thus allowing   better monitoring and better management of patients with thyroid pathology.

The EU TIRADS score is based on two elements: the cardinal signs and the accessory signs.

  1. Cardinal signs: the presence of a cardinal sign  places the nodule in the group  EU TIRADS 5  (according to the number of signs_ cardinals the risk varies between 26 and 87%).

  2. Accessory signs: in the absence of cardinal signs, echogenicity will determine the EU TIRADS 4, 3 and 2 score.

 

Accessory signs  will modulate the risk within each group (cancer risk of 17 – 0%).

This EU-TIRADS system includes:

  1. A lexicon containing key descriptive words, illustrated with an atlas (“typical” images)

  2. A score for malignancy risk stratification ranging from 1 to 5

  3. A standardized report with diagram

  4. Support recommendations

 

The EU TIRADS score is based on cardinal signs and accessory signs.

The cardinal signs will classify the nodule in a category and the accessory signs will modulate the risk  within each category.

The cardinal signs

  • The EU TIRADS 5 score

The cardinal signs of thyroid cancer are four in number:

  1. The shape of the nodule: not oval, thicker than wide and/or wide.

  2. The irregular contours of the nodule: spiculated or lobulated.

  3. The echogenicity of the nodule: marked hypoechogenicity.

  4. The microcalcifications.

The presence of one of the cardinal signs places the nodule in category 5.

The non-oval nodule shape

The non-oval shape is a suspicious sign  so the nodule is classified EU TIRADS  5.

Oval shape

Oval shape

Non-oval shape

Non-oval shape

The irregular contours of the nodule: spicules or lobules

It takes at least three spiculations or three  lobulations.

Regular contours

Lobulated contours

Spiculated contours

Lobulated contours

 

The strong hypoechogenicity

Strong hypoechogenicity

Strong hypoechogenicity

The strong hypoechogenicity of the nodule is a cardinal sign and the hypoechogenicity must be compared to the superficial muscle and not to the healthy thyroid parenchyma.

 

Microcalcifications

Hyperechoic, rounded or rarely linear pits measuring less than 1 mm in diameter without shadow cone or comet-tail artifact.

 

It is necessary to take into account their number and their grouping (at least 5).

Do not confuse the microcalcifications with the coloid type images at the level of the nodules.

Microcalcifications

Do not confuse microcalcifications and linear hyperechoic punctuations which have a comet-tail artefact, corresponding to the presence of intra-nodular colloid.

image 3.jpg

peripheral microcalcifications      Documents Dr Laila Daibes Rachid ( colegio Brasileiro de radiologia

image 2.jpg

peripheral microcalcifications      Documents Dr Laila Daibes Rachid ( colegio Brasileiro de radiologia

Macrocalcifications are not specific to malignancy and their presence must be related to the other ultrasound signs present.

The presence of cardinal signs at the level of a nodule means a very high risk of cancer which varies according to the number of signs present between 26% and 87%.

Beware of the fake EU TIRADS 5 score.

It is a highly hypoechoic nodule without any internal vascularization and this aspect is the consequence of the complete resorption of the intra-nodular haemorrhagic liquid component.

False EU-TIRADS 5 score (nodulehemorrhagic with a resorption complete fluid component)

False EU-TIRADS 5 score (nodulehemorrhagic with a resorption complete fluid component)

Accessory signs

Some accessory signs increase the risk of cancer and others decrease the risk.

These signs participate in the modulation of the risk within each EU-TIRADS score without modifying it.

 

Accessory signs that increase the risk are:​

Discontinuous peripheral macrocalcifications

Pathological elastography

Round shape

Central vascularization

Non-parallel orientation

 Extra capsular extension

Accessory signs that decrease the risk of malignancy are:

Fine and complete halo

Normal elastography

Peripheral vascularization

Mixed echostructure

colloidal granulation

flattened shape

 

The vascularization

Controversial value in the literature, vascularization is not retained in the EU TIRADS system.

The  vascularization provides few  diagnostic arguments, however in isoechoic solid nodules > 20 mm with strong central vascularization, the risk of follicular cancer increases, on the other hand a peripheral vasculature decreases the risk.

Cancerfollicular with strong peripheral and central vascularization

  • The EU TIRADS 4 score

 

Moderately hypoechoic nodule compared to the superficial muscle.

Theoretical risk  6-17%.

 

  • The EU TIRADS 3 score

 

Hyperechoic or isoechoic nodule.

Theoretical risk 2-4%.

  • The EU TIRADS 2 score

 

Cystic nodule colloidal type or a spongiform type nodule.

Theoretical risk 0%.

 

The standardized report must include a description of the nodule in 10 points with a diagram.

 

The standardized report must include a course of action for management.

Multinodular thyroids with the EU TIRADS score.

The strategy consists of:

  1. Look for high-risk nodules first (EU TIRADS5).

  2. Look for nodules at intermediate risk (EU TIRADS 4) and describe nodules > 5 mm.

  3. Look for low-risk nodules (EU TIRADS 3) and describe nodules > 10 mm.


The EU TIRADS score is based on echogenicity.

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